Research in the Dickstein lab focuses on the structural changes on neurons with ageing and disease. Our main research interests focus on Alzheimer's disease and Parkinson's disease, specifically targeting cells of the hippocampus and prefrontal cortex, areas crucial for cognition. We also investigate the effects of cancers and chemotherapy on neuronal and synapse integrity. We use a combination of transgenic mouse models, neuroanatomy, and confocal and electron microscopy to analyze the changes that neurons and synapses undergo during disease.