goate lab
Genetics of Neuropsychiatric Disease

Postdoctoral positions are available to work on the genetics and molecular neurobiology of Alzheimer's disease in the laboratory of Dr. Alison Goate, Director of the new Center on Alzheimer's disease at Icahn School of Medicine at Mount Sinai, a multidisciplinary center focused on understanding the molecular mechanisms underlying genetic risk for Alzheimer's disease and related disorders. Positions are available to work on several projects including whole genome sequencing to identify variants that protect APOE4 carriers from developing AD and whole exome sequencing in late onset AD families to identify novel genetic risk factors. Other projects use induced pluripotent stem cells and genome engineering to understand the mechanisms associated with risk or protection from AD associated with these novel genes. We have recently initiated studies on the role of PLD3 in risk for AD.

Applicants should hold a PhD in genetics, genomics, bioinformatics, computer science, statistical genetics or molecular neurobiology/stem cell biology. Please send a cover letter, curriculum vitae, and the names, phone numbers and e-mail addresses of three people who could provide letters of reference. Please submit your application materials online.