Dr. Hof is the Regenstreif Professor of Neuroscience and Vice-Chair for Translational Neuroscience of the Department of Neuroscience. In the Department, Dr. Hof also leads the Kastor Neurobiology of Aging Laboratories. His laboratory has extensive expertise in the pathology of neuropsychiatric disorders and has established an international reputation in quantitative approaches to neuroanatomy and studies of brain evolution.
|I received my Ph.D. in Biomedical and Comparative Veterinary Sciences from the University of Padova, Italy, where I began working on the organization of the cetacean cerebral cortex. My interests are in comparative brain evolution studying how different cortical organizations among mammals support similar functions. My current research focuses on the qualitative and quantitative analysis of the cytoarchitecture of frontal cortical regions, in a wide range of marine and terrestrial mammals, with a particular emphasis on neuronal specializations.
|As lab manager, I am responsible for the daily function of the
laboratory. I maintain the microscopes and computers of our
quantitative microscopy stations and train students, postdocs, and staff in their proper use. I also train laboratory personnel in a
variety of histologic techniques, which allows me to support the experimental work of our ongoing projects. I also catalogue and
manage Dr. Hof's extensive collection of mammalian brain specimens and prepared slides.
Bridget A. Wicinski
Pathological changes in the brain occurring in neurological and psychiatric diseases drive my research interest. My previous research has uncovered biochemical changes, specifically mitochondrial dysfunction and protein aggregation, occurring in animal and cellular models of various neurodegenerative disorders. I am currently investigating changes in neuronal structure in a rat model of Phelan-McDermid syndrome. My studies will compare dendritic and synaptic morphology in the hippocampus and prefrontal cortex of Shank3 rats to the wild-type using confocal and electron microscopic imaging. My goal is to contribute to understanding how deletions of the Shank3 protein affect synaptic structure and function in autism spectrum disorders.
Lab Location: Hess 10 - 302
Office Location: Hess 10 - 118
Office: (212) 824 - 9302
Lab: (212) 824 - 9172
Mount Sinai School of Medicine
Hess Center for Science & Medicine
1470 Madison Avenue
New York, NY 10029
Admin Phone: (212) 824 - 9326
Admin Fax: (646) 537 - 9585
|Mount Sinai School of Medicine
One Gustave L. Levy Place
New York, NY 10029