SELECTED PUBLICATIONS

For lay public summaries of some of the Center's latest scientific findings, please go to Latest Research Findings.

2016 SFN Abstracts.

2016

Noh KM, Allis CD, Li H (2016) Reading between the lines: "ADD"-ing histone and DNA methylation marks toward a new epigenetic "sum". ACS Chem Biol 11:554-563. PMCID: PMC4798892

Wenderski W, Maze I (2016) Histone turnover and chromatin accessibility: Critical mediators of neurological development, plasticity, and disease. Bioessays 38:410-419. NIHMS ID: 796891

Bagot TC, Cates HM, Purushothaman I, Vialou V, Heler EA, Labonté B, Peña CJ, Shen L, Nestler EJ (2016) Ketamine and imipramine reverse transcriptional signatures of susceptibility and induce resilience-specific gene expression profiles. Biol Psychiatry, in press. PMCID in progress

Koo JW, Labonté B, Engmann O, Calipari ES, Juarez B, Lorsch Z, Walsh JJ, Friedman AK, Yorgason JT, Han MH, Nestler EJ (2016) Essential role of mesolimbic brain-derived neurotrophic factor in chronic social stress-induced depressive behaviors. Biol Psychiatry, in press. PMCID: PMC4909591

Kundakovic M, Jiang Y, Kavanagh D, Dincer A, Brown L, Pothula V, Zharovsky E, Park R, Jacoboy R, Magro I, Kassim B, Wiseman J, Dang K, Sieberts SK, Roussos P, Fromer M, Harris B, Kipska BK, Peters MA, Sklar P, Akbarian S (2016) Practical guidelines for high-resolution epigenomic profiling of nucleosomal histones in postmortem human brain tissue. Biol Psychiatry, in press. NIHMS ID: 767217

Jakovcevski M, Akbarian S, Di Benedetto B (2016) Pharmacological modulation of astrocytes and the role of cell type-specific histone modifications for the treatment of mood disorders. Curr Opin Pharmacol 26:61-66. PMCID: PMC4716874

Heller EA, Hamilton PJ, Burek DD, Lombroso SI, Peña CJ, Nestler EJ (2016) Targeted epigenetic remodeling of the Cdk5 gene in nucleus accumbens regulates cocaine- and stress-evoked behavior. J Neurosci 36:4690-4697. PMCID: PMC4846670

Sun H, Martin JA, Werner CT, Wang ZJ, Damez-Werno DM, Scobie KN, Shao NY, Dias C, Rabkin J, Koo JW, Gancarz AM, Mouzon EA, Neve RL, Shen L, Dietz DM, Nestler EJ (2016) BAZ1B in nucleus accumbens regulates reward-related behaviors in response to distinct emotional stimuli. J Neurosci 36:3954-3961. PMCID: PMC4821908

Farrelly LA, Dill BD, Molina H, Birtwistle MR, Maze I (2016) Current proteomic methods to investigate dynamics of histone turnover in the central nervous system. Meth Enzymol, in press. NIHMS ID: 805696.

Friedman AK, Juarez B, Ku SM, Zhang HX, Calizo RC, Walsh JJ, Chaudhury D, Zhang S, Hawkins A, Dietz DM, Murrough JW, Ribadeneira M, Wong EH, Neve RL, Han MH (2016) KCNQ channel openers reverse depressive symptoms via an active resilience mechanism. Nat Commun 7:11671. PMCID: PMC4890180

Akbarian S and the PsychENCODE Consortium, Liu C, Knowles JA, Vaccarino FM, Farnham PJ, Crawford GE, Jaffe AE, Pinto D, Dracheva S, Geschwind DH, Mill J, Nairn AC, Abyzov A, Pochareddy S, Prabhakar S, Weissman S, Sullivan PF, State MW, Weng Z, Peters MA, White KP, Gerstein MB, Amiri A, Armoskus C, Ashley-Koch AE, Bae T, Beckel-Mitchener A, Berman BP, Coetzee GA, Coppola G, Francoeur N, Fromer M, Gao R, Grennan K, Herstein J, Kavanagh DH, Ivanov NA, Jiang Y, Kitchen RR, Kozlenkov A, Kundakovic M, Li M, Li Z, Liu S, Mangravite LM, Mattei E, Markenscoff-Papadimitriou E, Navarro FC, North N, Omberg L, Panchision D, Parikshak N, Poschmann J, Price AJ, Purcaro M, Reddy TE, Roussos P, Schreiner S, Scuderi S, Sebra R, Shibata M, Shieh AW, Skarica M, Sun W, Swarup V, Thomas A, Tsuji J, van Bakel H, Wang D, Wang Y, Wang K, Werling DM, Willsey AJ, Witt H, Won H, Wong CC, Wray GA, Wu EY, Xu X, Yao L, Senthil G, Lehner T, Sklar P, Sestan N (2015) The PsychENCODE project. Nat Neurosci 18:1707-1712. PMCID: PMC4675669

Golden SA, Christoffel DJ, Heshmati M, Guise K, Pfau ML, Aleyasin H, Hodes GE, Flanigan ME, Bregman D, Khibnik L,Tai J, Rebusi N, Krawitz B , Chaudhury D, Walsh JJ, Han MH, Shapiro ML, Russo SJ (2016) Ventral striatal projections to the lateral habenula modulate aggression reward. Nature 534:688-692. PMCID: PMC4930107

Bagot RC, Cates HM, Purushothaman I, Lorsch ZS, Walker DM, Wang JS, Huang XJ, Schlüter OM, Maze I, Peña CJ, Heller EA, Issler O, Wang MH, Song WM, Stein JL, Liu SC, Doyle MA, Scobie KN, Sun HS, Neve RL, Geschwind D, Dong Y, Shen L, Zhang B, Nestler EJ (2016) Circuit-wide transcriptional profiling reveals brain region-specific gene networks regulating depression susceptibility. Neuron 90:969-983. PMCID: PMC4896746

Ménard C, Hodes GE, Russo SJ (2016) Pathogenesis of depression: Insights from human and rodent studies. Neuroscience 321:138-162. PMCID: PMC4664582

Nestler EJ (2016) Transgenerational epigenetic contributions to stress responses: Fact or fiction? PLoS Biol 14:e1002426. PMCID: PMC4807775

Calipari ES, Bagot RC, Purushothaman I, Davidson TJ, Yorgason JT, Peña CJ, Walker DM, Pirpinias ST, Guise KG, Ramakrishnan C, Deisseroth K, Nestler EJ (2016) In vivo imaging identifies temporal signature of D1 and D2 medium spiny neurons in cocaine reward. Proc Natl Acad Sci U S A 113:2726-2731. PMCID: PMC4791010

2015

Caldarone BJ, Zachariou V, King SL (2015) Rodent models of treatment-resistant depression. Eur J Pharmacol 753:51-65. PMCID: PMC4423538

Allis CD (2015) "Modifying" my career toward chromatin biology. J Biol Chem 290:15904-15908. PMCID: PMC4481195

Hodes GE, Pfau ML, Purushothaman I, Ahn HF, Golden SA, Christoffel DJ, Magida J, Brancato A, Takahashi A, Flanigan ME, Ménard C, Aleyasin H, Koo JW, Lorsch ZS, Feng J, Heshmati M, Wang M, Turecki G, Neve R, Zhang B, Shen L, Nestler EJ, Russo SJ (2015) Sex differences in nucleus accumbens transcriptome profiles associated with susceptibility versus resilience to subchronic variable stress. J Neurosci 35:16362-16376. PMCID: PMC4679819

Jakovcevski M, Ruan H, Shen EY, Dincer A, Javidfar B, Ma Q, Peter CJ, Cheung I, Mitchell AC, Jiang Y, Lin CL, Pothula V, Stewart AF, Ernst P, Yao WD, Akbarian S (2015) Neuronal Kmt2a/Mll1 histone methyltransferase is essential for prefrontal synaptic plasticity and working memory. J Neurosci 35:5097-5108. PMCID: PMC4380991

Chaudhury D, Liu H, Han MH (2015) Neuronal correlates of depression. Cell Mol Life Sci 72(:4825-4848. PMCID: PMC4709015

Friedman AK, Han MH (2015) The use of Herpes Simplex Virus in ex vivo slice culture. Curr Protoc Neurosci 72:4.36.1-7. PMCID: PMC4514517

Nestler EJ (2015) ∆FosB: a transcriptional regulator of stress and antidepressant responses. Eur J Pharmacol 753:66-72. PMCID: PMC4380559

Shen EY, Ahern TH, Cheung I, Straubhaar J, Dincer A, Houston I, de Vries GJ, Akbarian S, Forger NG (2015) Epigenetics and sex differences in the brain: A genome-wide comparison of histone-3 lysine-4 trimethylation (H3K4me3) in male and female mice. Exp Neurol 268:21-29. PMCID: PMC4329105

Nestler EJ (2015) Role of the brain's reward circuitry in depression: Transcriptional mechanisms. Int Rev Neurobiol 124:151-170. PMCID: PMC4690450

Sun H, Damez-Werno DM, Scobie KN, Shao NY, Dias C, Rabkin J, Koo JW, Korb E, Bagot RC, Ahn FH, Cahill ME, Labonté B, Mouzon E, Heller EA, Cates H, Golden SA, Gleason K, Russo SJ, Andrews S, Neve R, Kennedy PJ, Maze I, Dietz DM, Allis CD, Turecki G, Varga-Weisz P, Tamminga C, Shen L, Nestler EJ (2015) ACF chromatin-remodeling complex mediates stress-induced depressive-like behavior. Nat Med 21:1146-1153. PMCID: PMC4598281

Christoffel DJ, Golden SA, Walsh JJ, Guise KG, Heshmati M, Friedman AK, Dey A, Smith M, Rebusi N, Pfau M, Ables JL, Aleyasin H, Khibnik LA, Hodes GE, Ben-Dor GA, Deisseroth K, Shapiro ML, Malenka RC, Ibanez-Tallon I, Han MH, Russo SJ (2015) Excitatory transmission at thalamo-striatal synapses mediates susceptibility to social stress. Nat Neurosci 18:962-964. PMCID: PMC4482771

Hodes GE, Kana V, Menard C, Merad M, Russo SJ (2015) Neuroimmune mechanisms of depression. Nat Neurosci 18:1386-1393. NIHMS NIHMS ID: 775272

Korb E, Herre M, Zucker-Scharff I, Darnell RB, Allis CD (2015) BET protein Brd4 activates transcription in neurons and BET inhibitor Jq1 blocks memory in mice. Nat Neurosci 18:1464-1473. PMCID: PMC4752120

Maze I, Wenderski W, Noh KM, Bagot RC, Tzavaras N, Purushothaman I, Elsässer SJ, Guo Y, Ionete C, Hurd YL, Tamminga CA, Halene T, Farrelly L, Soshnev AA, Wen D, Rafii S, Birtwistle MR, Akbarian S, Buchholz BA, Blitzer RD, Nestler EJ, Yuan ZF, Garcia BA, Shen L, Molina H, Allis CD (2015) Critical Role of Histone Turnover in Neuronal Transcription and Plasticity. Neuron 87:77-94. PMCID: PMC4491146

Vialou V, Thibault M, Kaska S, Cooper S, Gajewski P, Eagle A, Mazei-Robison M, Nestler EJ, Robison AJ (2015) Differential induction of FosB isoforms throughout the brain by fluoxetine and chronic stress. Neuropharmacology 99:28-37. PMCID: PMC4655122

Shen EY, Jiang Y, Mao W, Futai K, Hock H, Akbarian S (2015) Cognition and mood-related behaviors in L3mbtl1 null mutant mice. PLoS One 10:e0121252. PMCID: PMC4388653

Noh KM, Maze I, Zhao D, Xiang B, Wenderski W, Lewis PW, Shen L, Li H, Allis CD (2015) ATRX tolerates activity-dependent histone H3 methyl/phos switching to maintain repetitive element silencing in neurons. Proc Natl Acad Sci U S A 112:6820-6627. PMCID: PMC4460490

Dincer A, Gavin DP, Xu K, Zhang B, Dudley JT, Schadt EE, Akbarian S (2015) Deciphering H3K4me3 broad domains associated with gene-regulatory networks and conserved epigenomic landscapes in the human brain. Transl Psychiatry 5:e679. NIHMS NIHMS ID: 745280

Descalzi G, Ikegami D, Ushijima T, Nestler EJ, Zachariou V, Narita M (2015) Epigenetic mechanisms of chronic pain. Trends Neurosci 38:237-246. PMCID: PMC4459752

Bicks LK, Koike H, Akbarian S, Morishita H (2015) Prefrontal cortex and social cognition in mouse and man. Front Psychol. 2015 Nov 26;6:1805. PMCID: PMC4659895

2014

Mitchell AC, Bharadwaj R, Whittle C, Krueger W, Mirnics K, Hurd Y, Rasmussen T, Akbarian S (2014) The genome in three dimensions: a new frontier in human brain research. Biol Psychiatry 75:961-969. PMCID: PMC3925763

Bagot RC, Labonté B, Peña CJ, Nestler EJ (2014) Epigenetic signaling in psychiatric disorders: stress and depression. Dialogues Clin Neurosci 16:281-295. PMCID: PMC4214172

Vialou V, Bagot RC, Cahill ME, Ferguson D, Robison AJ, Dietz DM, Fallon B, Mazei-Robison M, Ku SM, Harrigan E, Winstanley CA, Joshi T, Feng J, Berton O, Nestler EJ (2014) Prefrontal cortical circuit for depression- and anxiety-related behaviors mediated by cholecystokinin: role of ΔFosB. J Neurosci 34:3878-3887. PMCID: PMC3951691

Heller EA, Cates HM, Peña CJ, Sun H, Shao N, Feng J, Golden SA, Herman JP, Walsh JJ, Mazei-Robison M, Ferguson D, Knight S, Gerber MA, Nievera C, Han MH, Russo SJ, Tamminga CS, Neve RL, Shen L, Zhang HS, Zhang F, Nestler EJ (2014) Locus-specific epigenetic remodeling controls addiction- and depression-related behaviors. Nat Neurosci 17:1720-1727. PMCID: PMC4241193

Maze I, Chaudhury D, Dietz DM, Von Schimmelmann M, Kennedy PJ, Lobo MK, Sillivan SE, Miller ML, Bagot RC, Sun H, Turecki G, Neve RL, Hurd YL, Shen L, Han MH, Schaefer A, Nestler EJ (2014) G9a influences neuronal subtype specification in striatum. Nat Neurosci 17:533-539. PMCID: PMC3972624

Maze I, Shen L, Zhang B, Garcia BA, Shao N, Mitchell A, Sun H, Akbarian S, Allis CD, Nestler EJ (2014) Analytical tools and current challenges in the modern era of neuroepigenomics. Nat Neurosci 17:1476-1490. PMCID: PMC4262187

Walsh, J.J., Friedman, A.K., Sun, H.S., Heller, E.A., Ku, S.M., Juarez, B., Burnham, V.L., Mazei-Robison, M.S., Ferguson, D., Golden, S.A., Koo, J.W., Chaudhury, D., Christoffel, D.J., Pomeranz, L., Friedman, J.M., Russo, S.J., Nestler, E.J., and Han, M.H. (2014) Stress gates neural activation of BDNF in the mesolimbic reward pathway. Nat. Neurosci. 17:27-29. PMCID: PMC3984932

Maze I, Noh KM, Soshnev AA, Allis CD (2014) Every amino acid matters: essential contributions of histone variants to mammalian development and disease. Nat Rev Genet 15:259-271. PMCID: PMC4082118

Dias C, Feng J, Sun H, Shao NY, Mazei-Robison MS, Damez-Werno D, Scobie K, Bagot R, LaBonté B, Ribeiro E, Liu X, Kennedy P, Vialou V, Ferguson D, Peña C, Calipari ES, Koo JW, Mouzon E, Ghose S, Tamminga C, Neve R, Shen L, Nestler EJ (2014) β-catenin mediates stress resilience through Dicer1/microRNA regulation. Nature 516:51-55. PMCID: PMC4257892

Bharadwaj R, Peter CJ, Jiang Y, Roussos P, Vogel-Ciernia A, Shen EY, Mitchell AC, Mao W, Whittle C, Dincer A, Jakovcevski M, Pothula V, Rasmussen TP, Giakoumaki SG, Bitsios P, Sherif A, Gardner PD, Ernst P, Ghose S, Sklar P, Haroutunian V, Tamminga C, Myers RH, Futai K, Wood MA, Akbarian S (2014) Conserved higher-order chromatin regulates NMDA receptor gene expression and cognition. Neuron 84:997-1008. PMCID: PMC4258154

Robison AJ, Vialou V, Sun HS, Labonte B, Golden SA, Dias C, Turecki G, Tamminga C, Russo S, Mazei-Robison M, Nestler EJ (2014) Fluoxetine epigenetically alters the CaMKIIα promoter in nucleus accumbens to regulate ΔFosB binding and antidepressant effects. Neuropsychopharmacology 39:1178-1186. PMCID: PMC3957112

Sun H, Kennedy PJ, Nestler EJ (2014) Epigenetics of the depressed brain: role of histone acetylation and methylation. Neuropsychopharmacology, 38:124 - 137. PMCID: PMC3521990

Walsh JJ, Han MH (2014) The heterogeneity of ventral tegmental area neurons: Projection functions in a mood-related context. Neuroscience 282C:101-108. PMCID: PMC4339667

Friedman AK, Walsh JJ, Juarez B, Ku SM, Chaudhury D, Wang J, Li X, Dietz DM, Pan N, Vialou VF, Neve RL, Yue Z, Han MH (2014) Enhancing depression mechanisms in midbrain dopamine neurons achieves homeostatic resilience. Science 344:313-319. PMCID: PMC4334447

Tamminga CA (2014) Approaching human neuroscience for disease understanding. World Psychiatry 13:41-43. PMCID: PMC3918015

Shen L, Shao NY, Nestler EJ (2014) ngs.plot: Quick mining and visualization of next-generation sequencing data by integrating genomic databases. BMC Genomics 15:284. PMCID: PMC4028082

2013

Akbarian, S. and Halene, T. (2013) The neuroepigenetics of suicide. Am. J. Psychiatry 170:462 - 465. PMCID: PMC4055567

Vialou V, Feng J, Robison AJ, Nestler EJ (2013) Epigenetic mechanisms of depression and antidepressant drug action. Annu Rev Pharmacol Toxicol. 53:59 - 87. PMCID: PMC3711377

Jakovcevski, M., Bharadwaj, R., Straubhaar, J., Gao, G., Gavin, D.P., Jakovcevski, I., Mitchell, A.C., and Akbarian, S. (2013) Prefrontal cortical dysfunction after overexpression of histone deacetylase 1. Biol. Psychiatry 74:696 - 705. PMCID: PMC3797203

Suri D, Veenit V, Sarkar A, Thiagrarjan D, Kumar A, Nestler EJ, Galande S, Vaidya VA (2013) Early stress evokes age - dependent biphasic changes in hippocampal neurogenesis, Bdnf expression and cognition. Biol. Psychiatry 73:658 - 666. PMCID: PMC4051354

Warren BL, Vialou VF, Iñiguez SD, Alcantara LF, Wright KN, Feng J, Kennedy PJ, LaPlant Q, Shen L, Nestler EJ, Bolaños - Guzman C (2013) Neurobiological sequelae of witnessing stressful events in adult mice. Biol. Psychiatry 73:7 - 14. PMCID: PMC3498570

Shen L, Choi I, Nestler EJ, Won KJ (2013) Human transcriptome and chromatin modifications: An ENCODE perspective. Genomics Informatics 11:60-67. PMCID: PMC3704928

Lobo MK, Zaman S, Damez-Werno DM, Koo JW, Bagot RC, DiNieri JA, Nugent A, Finkel E, Chaudhury D, Chandra R, Riberio E, Rabkin J, Mouzon E, Cachope R, Cheer JF, Han MH, Dietz DM, Self DW, Hurd YL, Vialou V, Nestler EJ. (2013) ΔFosB induction in striatal medium spiny neuron subtypes in response to chronic pharmacological, emotional, and optogenetic stimuli. J Neurosci 33:18381-18395. PMCID: PMC3834048

Akbarian S, Beeri MS, Haroutunian V (2013) Epigenetic determinants of healthy and diseased brain aging and cognition. JAMA Neurol 9:1 - 8. PMCID: PMC3932340

Golden, S.A., Christoffel, D.J., Heshmati, M., Hodes, G.E., Magida, J., Davis, K., Cahill, M.E., Dias, C., Ribeiro, E., Ables, J.L., Kennedy, P.J., Robison, A.J., Gonzalez-Maeso, J., Neve, R.L., Turecki, G., Ghose, S., Tamminga, C.A., and Russo, S.J. (2013) Epigenetic regulation of RAC1 induces synaptic remodeling in stress disorders and depression. Nat. Med. 19:337 - 344. PMCID: PMC3594624

Russo, S.J. and Nestler, E.J. (2013) The brain reward circuitry in mood disorders. Nat. Rev. Neurosci. 14:609-625. PMCID: PMC3867253

Chaudhury D, Walsh JJ, Friedman AK, Juarez B, Ku SM, Koo JW, Ferguson D, Tsai HC, Pomeranz L, Christoffel DJ, Nextow AR, Ekstrand M, Domingos A, Mazei-Robison M, Mouzon E, Lobo MK, Neve RL, Friedman JM, Russo SJ, Deisseroth K, Nestler EJ, Han MH (2013) Rapid regulation of depression - related behaviors by control of midbrain dopamine neurons. Nature 493:532 - 536. PMCID: PMC3554860

Maze I, Noh KM, Allis CD (2013) Histone regulation in the CNS: basic principles of epigenetic plasticity. Neuropsychopharmacology 38:3 - 22. PMCID: PMC3521967

Shen, L., Shao, N.Y., Liu, X.C., Maze, I., Feng, J., and Nestler, E.J. (2013) diffReps: Detecting differential chromatin modification sites from ChIP-seq data with biological replicates. PLoS One 8:e65598. PMCID: PMC3677880

Casadio F, Lu X, Pollock SB, LeRoy G, Garcia BA, Muir TW, Roeder RG, Allis CD (2013) H3R42me2a is a histone modification with positive transcriptional effects. Proc Natl Acad Sci U S A 110:14894-14899. PMCID: PMC3773778

Stratinaki, M., Varidaki, A., Mitsi, V., Ghose, S., Magida, J., Dias, C., Russo, S.J., Vialou, V., Caldarone, B.J., Tamminga, C.A., Nestler, E.J., and Zachariou, V. (2013) Regulator of G protein signaling 4 is a crucial modulator of antidepressant drug action in depression and neuropathic pain models. Proc. Natl. Acad. Sci. USA 110:8254 - 8259. PMCID: PMC3657820

Lewis, P.W., Müller, M.M., Koletsky, M.S., Cordero, F., Lin, S., Banaszynski, L.A., Garcia, B.A., Muir, T.W., Becher, O.J., and Allis, C.D. (2013) Inhibition of PRC2 activity by a gain - of - function H3 mutation found in pediatric glioblastoma. Science 340:857 - 861. PMCID: PMC3951439

Shulha HP, Cheung I, Guo Y, Akbarian S, Weng Z (2013) Coordinated cell type-specific epigenetic remodeling in prefrontal cortex begins before birth and continues into early adulthood. PLoS Genet 9:e1003433. PMCID: PMC3623761

2012

Lobo MK, Nestler EJ, Covington HE 3rd (2012) Potential utility of optogenetics in the study of depression. Biol Psychiatry 71:1068-1074. PMCID: PMC3738208

Muschamp JW, Nemeth CL, Robison AJ, Nestler EJ, Carlezon WA Jr (2012) ΔFosB enhances the rewarding effects of cocaine while reducing the pro-depressive effects of the kappa-opioid receptor agonist U50488. Biol Psychiatry 71:44-50. PMCID: PMC3230776

Jakovcevski M, Akbarian S (2012) Epigenetic mechanisms in neurological disease. Nat Med 18:1194-1204. PMCID: PMC3596876

Liu J, Dietz K, DeLoyht JM, Pedre X, Kelkar D, Kaur J, Vialou V, Lobo MK, Dietz DM, Nestler EJ, Dupree J, Casaccia P (2012) Impaired adult myelination in the prefrontal cortex of socially isolated mice. Nat Neurosci 15:1621-1623. PMCID: PMC3729624

Russo SJ, Murrough JW, Han MH, Charney DS, Nestler EJ (2012) Neurobiology of resilience. Nat Neurosci 15:1475-1484. PMCID: PMC3580862

Han MH, Friedman AK (2012) Virogenetic and optogenetic mechanisms to define potential therapeutic targets in psychiatric disorders. Neuropharmacology 62:89-100. PMCID: PMC3205991

Christoffel DJ, Golden SA, Heshmati M, Graham A, Birnbaum S, Neve RL, Hodes GE, Russo SJ (2012) Effects of inhibitor of κB kinase activity in the nucleus accumbens on emotional behavior. Neuropsychopharmacology 37:2615-2623. PMCID: PMC3473326

Dietz DM, Nestler EJ (2012) From father to offspring: paternal transmission of depressive-like behaviors. Neuropsychopharmacology 37:311-312. PMCID: PMC3238062

Shulha HP, Crisci JL, Reshetov D, Tushir JS, Cheung I, Bharadwaj R, Chou HJ, Houston IB, Peter CJ, Mitchell AC, Yao WD, Myers RH, Chen JF, Preuss TM, Rogaev EI, Jensen JD, Weng Z, Akbarian S (2012) Human-specific histone methylation signatures at transcription start sites in prefrontal neurons. PLoS Biol 10:e1001427. PMCID: PMC3502543

2011

Dietz DM, LaPlant Q, Watts EL, Hodes GE, Russo SJ, Feng J, Oosting RS, Nestler EJ (2011) Paternal transmission of stress-induced pathologies. Biol Psychiatry 70:408 - 414. PMCID: PMC3217197

Covington HE, Maze I, Sun HS, Wu EY, Dietz D, Lobo MK, Ghose S, Neve R, Tamminga CA, Nestler EJ (2011) A role for repressive histone methylation in cocaine-induced vulnerability to stress. Neuron 71:656 - 670. PMCID: PMC3163060

Nestler EJ (2011) Hidden switches in the mind. Scientific American, Dec. 2011, pp. 76 - 83. PMCID: PMC4214253

Peter CJ, Akbarian S (2011) Balancing histone methylation activities in psychiatric disorders. Trends Mol Med 17:372 - 379. PMCID: PMC3134618