neuro
nestler lab
Laboratory of Molecular Psychiatry

SELECTED PUBLICATIONS

2016

Calipari ES, Juarez B,, Morel C, Walker DM, Cahill ME, Ribeiro E, Roman-Ortiz C, Ramakrishnan C, Deisseroth K,Han MH, Nestler EJ. Dopaminergic dynamics underlying sex-specific cocaine reward. Nat Commun. 2017 Jan 10;8:13877. doi: 10.1038/ncomms13877.
  Bagot RC, Cates HM, Purushothaman I, Lorsch ZS, Walker DM, Wang J, Huang X, Schlüter OM, Maze I, Peña CJ, Heller EA, Issler O, Wang M, Song WM, Stein JL, Liu X, Doyle MA, Scobie KN, Sun HS, Neve RL, Geschwind D, Dong Y, Shen L, Zhang B, Nestler EJ.Circuit-wide Transcriptional Profiling Reveals Brain Region-Specific Gene Networks Regulating Depression Susceptibility.Neuron. 2016 May 11. pii: S0896-6273(16)30074-5. doi: 10.1016/j.neuron.2016.04.015. [Epub ahead of print]
  Nestler EJ.Transgenerational Epigenetic Contributions to Stress Responses: Fact or Fiction?PLoS Biol. 2016 Mar 25;14(3):e1002426. doi: 10.1371/journal.pbio.1002426. eCollection 2016.
  Cahill ME, Bagot RC, Gancarz AM, Walker DM, Sun H, Wang ZJ, Heller EA, Feng J, Kennedy PJ, Koo JW, Cates HM, Neve RL, Shen L, Dietz DM, Nestler EJ. Bidirectional Synaptic Structural Plasticity after Chronic Cocaine Administration Occurs through Rap1 Small GTPase Signaling.Neuron. 2016 Feb 3;89(3):566-82. doi: 10.1016/j.neuron.2016.01.031.
  Calipari ES, Bagot RC, Purushothaman I, Davidson TJ, Yorgason JT, Peña CJ, Walker DM, Pirpinias ST, Guise KG, Ramakrishnan C, Deisseroth K, Nestler EJ. In vivo imaging identifies temporal signature of D1 and D2 medium spiny neurons in cocaine reward. Proc Natl Acad Sci U S A. 2016 Mar 8;113(10):2726-31. doi: 10.1073/pnas.1521238113. Epub 2016 Feb 1.

2015

Sun, H.S., Damez-Werno, D., Scobie, K.N., Shao, N.Y., Dias, C., Rabkin, J., Koo, J.W., Korb, E., Bagot, R.C., Cahill, M., Labonté, B., Mouzon, E., Heller, E.A., Cates, H., Golden, S.A., Gleason, K., Russo, S.J., Andrews, S., Neve, R., Kennedy, P.J., Maze, I., Dietz, D.M., Allis, C.D., Turecki, G., Varga-Weisz, P., Tamminga, C., Shen, L., and Nestler, E.J. (2015) ACF chromatin remodeling complex mediates stress-induced depressive-like behavior. Nat. Med. 21:1146-1153.
Ferguson, D., Shao, N.Y., Heller, E., Feng, F., Neve, R., Kim, H.D., Call, T., Magazu, S., Shen, L., and Nestler, E.J. (2015) SIRT1-FOXO3a regulate cocaine actions in the nucleus accumbens. J. Neurosci. 35:3100-3111.
Koo, J.W., Mazei-Robison, M.S., LaPlant, Q., Egervari, G., Braunscheidel, K.M., Adank, D.N., Ferguson, D., Feng, J., Sun, H.S., Scobie, K.N., Damez-Werno, D.M., Ribeiro, E., Peña, C.J., Walker, D., Bagot, R.C., Cahill, M.E., Anderson, S.A.R., Labonté, B., Hodes, G.E., Browne, H., Chadwick, B., Robison, A.J., Vialou, V.F., Dias, C., Lorsch, Z., Mouzon, E., Lobo, M.K., Dietz, D.M., Russo, S.J., Neve, R.L., Hurd, Y.L., and Nestler, E.J. (2015) Epigenetic basis of opiate suppression of Bdnf gene expression in the ventral tegmental area. Nat. Neurosci. 18:415-422.
Feng, J., Shao, N.Y., Szulwach, K.E., Vialou, V., Huynh, J., hong, C., Le, T., Ferguson, D., Cahill, M.E., Li, Y.J., Koo, J.W., Ribeiro, E., Labonté, B., Laitman, B.M., Estey, D., Stockman, V., Kennedy, P., Courousse, T., Mensah, I., Turecki, G., Faull, K.F., Song, H.J., Fan, G.P., Casaccia, P., Shen, L., Jin, P., and Nestler, E.J. (2015) Role of Tet1 and 5-hydroxymethylcytosine in cocaine action. Nat. Neurosci. 18:536-544.
Bagot, R.C., Parise, E.M., Peña, C.J., Zhang, H.X., Maze, I., Chaudhury, D., Persaud, B., Cachope, R., Bolaños-Guzman, C.A., Cheer, J., Deisseroth, K., Han, M.H., and Nestler, E.J. (2015) Ventral hippocampal afferents to the nucleus accumbens regulate susceptibility to depression. Nat. Commun. 6:7062.

2014

Heller EA, Cates HM, Peña CJ, Sun H, Shao N, Feng J, Golden SA, Herman JP, Walsh JJ, Mazei-Robison M, Ferguson D, Knight S, Gerber MA, Nievera C, Han MH6, Russo SJ, Tamminga CS, Neve RL, Shen L, Zhang HS, Zhang F, Nestler EJ. Locus-specific epigenetic remodeling controls addiction- and depression-related behaviors.Nat Neurosci. 2014 Oct 27. doi: 10.1038/nn.3871.
Dias C, Feng J, Sun H, Shao NY, Mazei-Robison MS, Damez-Werno D, Scobie K, Bagot R, LaBonté B, Ribeiro E, Liu X, Kennedy P, Vialou V, Ferguson D, Peña C, Calipari ES, Koo JW, Mouzon E, Ghose S, Tamminga C, Neve R, Shen L, Nestler EJ. ß-catenin mediates stress resilience through Dicer1/microRNA regulation. Nature. 2014 Nov 12. doi: 10.1038/nature13976. [Epub ahead of print]
Maze, I., Shen, L., Zhang, B., Garcias, B.A., Shao, N.Y., Mitchell, A., Sun, H.S., Akbarian, S., Allis, C.D., and Nestler, E.J. (2014) Analytical tools and current challenges in the modern era of neuroepigenomics. Nat. Neurosci. 17:1476-1490.
Shen, L., Shao, N.Y., and Nestler, E.J. (2014) ngs.plot: Quick mining and visualization of next-generation sequencing data by integrating genomic databases. BMC Genomics 15:284.
Vialou, V., Bagot, R.C., Cahill, M.E., Ferguson, D., Robison, A.J., Dietz, D.M., Fallon, B., Mazei-Robison, M., Ku, S.M., Harrigan, E., Winstanley, C.A., Joshi, T., Feng, J., Berton, O., and Nestler, E.J. (2014) Prefrontal cortical circuit for depression- and anxiety-related behaviors mediated by cholecystokinin: role of ΔFosB. J. Neurosci. 34:3878-3887.
Peña, C.J., Bagot, R.C., Labonté, B., and Nestler, E.J. (2014) Epigenetic signaling in psychiatric disorders. J. Mol. Biol. 426:3389-3412.
Maze, I., Noh, K.M., Soshnev, A.A., Allis, C.D. (2014) Every amino acid matters: essential contributions of histone variants to mammalian development and disease. Nat. Rev. Genet.
Mitchell, A.C., Bharadwaj, R., Whittle, C., Krueger, W., Mirnics, K., Hurd, Y., Rasmussen, T., and Akbarian, S. (2014) The genome in three dimensions: a new frontier in human brain research. Biol. Psychiatry.

Dong Y, Nestler EJ. The neural rejuvenation hypothesis of cocaine addiction. Trends Pharmacol Sci. 2014 Aug;35(8):374-83.

Feng J, Wilkinson M, Liu X, Purushothaman I, Ferguson D, Vialou V, Maze I, Shao N, Kennedy P, Koo J, Dias C, Laitman B, Stockman V, LaPlant Q, Cahill ME, Nestler EJ, Shen L. Chronic cocaine-regulated epigenomic changes in mouse nucleus accumbens. Genome Biol. 2014 Apr 22;15(4):R65.

Maze I, Chaudhury D, Dietz DM, Von Schimmelmann M, Kennedy PJ, Lobo MK, Sillivan SE, Miller ML, Bagot RC, Sun H, Turecki G, Neve RL9, Hurd YL, Shen L, Han MH, Schaefer A4, Nestler EJ. G9a influences neuronal subtype specification in striatum. Nat Neurosci. 2014 Apr;17(4):533-9.

Scobie KN, Damez-Werno D, Sun H, Shao N, Gancarz A, Panganiban CH, Dias C, Koo J, Caiafa P, Kaufman L, Neve RL, Dietz DM, Shen L, Nestler EJ. Essential role of poly(ADP-ribosyl)ation in cocaine action. Proceedings of the National Academy of Sciences of the United States of America 2014 Feb; 111(5).

2013

 

Kennedy, P.J., Robison, A.J., Maze, I., Feng, J., Badimon, A., Bassel-Duby, R., Olson, E.N., and Nestler, E.J. (2012) HDAC1 inhibition blocks cocaine-induced plasticity through targeted changes in histone methylation. Nat. Neurosci. 16:434-440.

  Robison, A.J., Vialou, V., Mazei-Robison, M., Feng, J., Kourrich, S., Collins, M., Wee, S.M., Koob, G., Turecki, G., Neve, R., Thomas, M., and Nestler, E.J. (2013) Behavioral and structural responses to chronic cocaine require a feed-forward loop involving ∆FosB and CaMKII in the nucleus accumbens shell. J. Neurosci. 33:4295-4307.
Chaudhury, D., Walsh, J.J. Friedman, A.K., Juarez, B., Ku, S.M., Koo, J.W., Ferguson, D., Tsai, H.-C., Pomeranz, L., Christoffel, D.J., Nextow, A.R., Ekstrand, M., Domingos, A., Mazie-Robison, M., Mouzon, E., Lobo, M.K., Neve, R.L., Friedman, J.M., Russo, S.J., Deisseroth, K., Nestler, E.J., and Han, M.-H. (2012) Rapid regulation of depression-related behaviors by control of midbrain dopamine neurons. Nature 493:532-536.

2012

Dietz, D.M., Sun, H.S., Lobo, M.K., Cahill, M.E., Chadwick, B., Gao, V., Koo, J.W., Mazei-Robison, M.S., Dias, C., Maze, I., Damez-Werno, D., Dietz, K.C., Scobie, K.N., Ferguson, D., Christofell, D., Ohnishi, Y., Hodes, G.E., Zheng, Y., Neve, R.L., Hahn, K.M., Russo, S.J., and Nestler, E.J. (2012) Essential for Rac1 in cocaine-induced structure plasticity of nucleus accumbens neurons. Nature Neurosci. 15:891-896.
Koo, J.W., Mazei-Robison, M.S., Chaudhury, D., Juarez, B., LaPlant, Q., Ferguson, D., Feng, J., Sun, H.S., Scobie, K.N., Damez-Werno, D., Crumiller, M., Ohnishi, Y.N., Ohnishi, Y.H., Mouzon, E., Dietz, D.M., Lobo, M.K., Neve, R.L., Russo, S.J., Han, M.H., and Nestler, E.J. (2012) BDNF is a negative modulator of morphine action. Science 338:124-128.
 

Vialou, V., Feng, J., Robison, A.J., and Nestler, E.J. (2012) Epigenetic mechanisms of depression and antidepressant action. Annu. Rev. Pharmacol. Toxicol. 53:59-87.

Russo, S.J., Murrough, J.W., Han, M.H., Charney, D.S., and Nestler, E.J. (2012) Neurobiology of resilience. Nature Neurosci. 15:1475-1484.

2011

Covington, H.E. III, Maze, I., Sun, H.S., Wu, E.Y., Dietz, D., Lobo, M.K., Ghose, S., Neve, R., Tamminga, C.A., and Nestler, E.J. (2011) A role for repressive histone methylation in cocaine-induced vulnerability to stress. Neuron 71:656-670.

Dietz, D.M., LaPlant, Q., Watts, E.L., Hodes, G.E., Russo, S.J., Feng, J., Oosting, R.S., and Nestler, E.J. (2011) Paternal transmission of stress-induced pathologies. Biol. Psychiatry 70:408-414.

Mazei-Robison, M.S., Koo, J.W., Friedman, A., Lansink, C.S., Robison, A.J., Vinish, M., Krishnan, V., Kim, S., Siuta, M.A., Galli, M.A., Niswender, K.D., Appasani, R., Horvath, M.C., Neve, R.L., Worley, P.F., Snyder, S.H., Hurd, Y.L., Cheer, J.F., Han, M.H., Russo, S.J., and Nestler, E.J. (2011) Role for mTOR signaling and neuronal activity in morphine-induced adaptations in ventral tegmental area dopamine neurons. Neuron 72:977-990.
Robison, A.J. and Nestler, E.J. (2011) Transcriptional and epigenetic mechanisms of addiction. Nature Rev. Neurosci. 12:623-637.
  Nestler EJ (2011) Hidden switches in the mind. Scientific American, Dec 2011, pp. 76-83.
Maze, I., Feng, J., Wilkinson, M.B., Sun, H.S., Shen, L., and Nestler, E.J. (2011) Cocaine dynamically regulates heterochromatin and repetitive element unsilencing in nucleus accumbens. Proc. Natl. Acad. Sci. USA 108:3035-3040.

2010

Russo, S.J., Dietz, D.M., Dumitriu, D., Morrison, J.H., Malenka, R.C., and Nestler, E.J. (2010) The addicted synapse:  Mechanisms of synaptic and structural plasticity in nucleus accumbens. Trends Neurosci. 33:267-276.
Lobo, M.K., Covington, H.E. III, Chaudhury, D., Friedman, A.K., Sun, H.S., Damez-Werno, D., Dietz, D., Zaman, S., Koo, J.W., Kennedy, P.J., Mouzon, E., Mogri, M., Neve, R.L., Deisseroth, K., Han, M.H., and Nestler, E.J. (2010) Cell type specific loss of BDNF signaling mimics optogenetic control of cocaine reward. Science 330:385-390.
Maze, I., Covington, H.E. III, Dietz, D.M., LaPlant, Q., Renthal, W., Russo, S.J., Mechanic, M., Mouzon, E., Neve, R.L., Haggarty, S.J., Ren, Y.H., Sampath, S.C., Hurd, Y.L., Greengard, P., Tarakovsky, A., Schaefer, A., and Nestler, E.J. (2010) Essential role of the histone methyltransferase G9a in cocaine-induced plasticity. Science 327:213-216.

2009

Renthal, W., Kumar, A., Xiao, G.H., Wilkinson, M., Convington, H.E. III, Mze, I., Sikder, D., Robison, A.J., LaPlant, Q., Dietz, D.M., Russo, S.J., Vialou, V., Chakravarty, S., Kodadek, T.J., Stack, A., Kabbaj, M., and Nestler, E.J. (2009) Genome wide analysis of chromatin regulation by cocaine reveals a novel role for sirtuins. Neuron 62:335-348.
Wallace, D.L., Han, M.H., Graham, D.L., Green, T.A., Vialou, V., Iniguez, S.D., Cao, J.L., Chakravarty, S., Kumar, A., Krishnan, V., Neve, R.L., Cooper, D.C., Bolaños, C.A., Barrot, M., McClung, C.A., and Nestler, E.J. (2009) CREB Regulation of nucleus accumbens excitability mediates social isolation-induced behavioral deficits. Nature Neurosci. 12:200-209.

2008

Lutter, M., Sakata, I., Osborne-Lawrence, S., Rovinsky, S.A., Anderson, J.G., Jung, S., Birnbaum, S., Yanagisawa, M., Elmquist, J.K., Nestler, E.J., and Zigman, J.M. (2008) The orexigenic hormone ghrelin defends against depressive symptoms of chronic stress. Nature Neurosci. 11:752-753.
Pulipparacharuvil, S., Renthal, W., Hale, C.F., Taniguchi, M., Xiao, G.H., Kumar, A., Russo, S.J., Sikder, D., Dewey, C.M., Davis, M.M., Greengard, P., Nairn, A.C., Nestler, E.J., and Cowan, C.W. (2008) Cocaine regulates MEF2 to control synaptic and behavioral plasticity. Neuron 59:621-633.
Krishnan, V. and Nestler, E.J. (2008) The molecular neurobiology of depression. Nature 455:894-902.

2007

Russo, S.J., Bolanos, C.A., Theobald, D.E., DeCarolis, N.A., Renthal, W.R., Kumar, A., Winstanley, C.A., Renthal, N.E., Wiley, M.D., Self, D.W., Russell, D.S., Neve, R.L., Eisch, A.J., and Nestler, E.J. (2007) The IRS2-Akt pathway in midbrain dopaminergic neurons regulates behavioral and cellular responses to opiates. Nature Neurosci. 10:93-99.
Tsankova, N., Renthal, W., Kumar, A., and Nestler, E.J. (2007) Epigenetic regulation in psychiatric disorders. Nature Rev. Neurosci. 8:355-367.
Krishnan, V., Han, M.-H., Graham, D.L., Berton, O., Renthal, W., Russo, S.J., LaPlant, Q., Graham, A., Lutter, M., Lagace, D.C., Ghose, S., Reister, R., Tannous, P., Green, T.A., Neve, R.L., Chakravarty, S., Kumar, A., Eisch, A.J., Self, D.W., Lee, F.S., Tamminga, C.A., Cooper, D.C., Gershenfeld, H.K., and Nestler, E.J. (2007) Susceptibility and resistance to social defeat are mediated through molecular adaptations in brain reward regions. Cell 131:391-404.
Renthal, W., Maze, I., Krishnan, V., Covington, H.E., Xiao, G.H., Kumar, A., Russo, S.J., Graham, A., Tsankova, N., Kerstetter, K.A., Kippin, T.E., Neve, R.L., Haggarty, S.J., McKinsey, T.A., Bassel-Duby, R., Olson, E.N., and Nestler, E.J. (2007) Histone deacetylase 5 epigenetically controls behavioral adaptations to chronic emotional stimuli. Neuron 56:517-529.

2006

Berton, O., McClung, C.A., DiLeone, R.J., Krishnan, V., Russo, S., Graham, D., Tsankova, N.M., Bolanos, C.A., Rios, M., Monteggia, L.M., Self, D.W., and Nestler, E.J. (2006) Essential role of BDNF in the mesolimbic dopamine pathway in social defeat stress. Science 311:864-868.
Zachariou, V., Bolanos, C.A., Selley, D.E., Theobald, D., Cassidy, M.P., Kelz, M.B., Shaw-Lutchmann, T., Berton, O., Sim-Selley, L.J., DiLeone, R.J., Kumar, A., and Nestler, E.J. (2005) ΔFosB: An essential role for ΔFosB in the nucleus accumbens in morphine action. Nature Neurosci. 9:205-211.
Tsankova, N.M., Berton, O., Renthal, W., Kumar, A., Neve, R.L., and Nestler, E.J. (2006) Sustained chromatin regulation in hippocampus in a mouse model of depression and antidepressant action: A novel role for HDAC5. Nature Neurosci. 9:519-525.

2005

McClung, C.A., Sidiropoulou, K., Vitaterna, M., Takahashi, J.S., White, F.J., Cooper, D.C., and Nestler, E.J. (2005) Regulation of dopaminergic transmission and cocaine reward by the Clock gene. Proc. Natl. Acad. Sci. USA 102:9377-9381.
Nestler, E.J. (2005) Is there a common molecular pathway for addiction. Nature Neurosci. 8:1445-1449
Kumar, A., Choi, K.-H., Renthal, W., Tsankova, N.M., Theobald, D.E.H., Truong, H.-T., Russo, S.J., LaPlant, Q., Whistler, K., Neve, R.L., Self, D.W., and Nestler, E.J. (2005) Chromatin remodeling is a key mechanism underlying cocaine-induced plasticity in striatum. Neuron 48:303-314.
Berton, O. and Nestler, E.J. (2005) New approaches to antidepressant drug discovery: Beyond monoamines. Nature Rev. Neurosci. 7:137-151.

2004

Nestler, E.J. and Malenka, R.C. (2004) The addiction brain. Scientific American, March 2004, pp. 78-85.
Monteggia, L.M., Barrot, M., Powell, C.M., Berton, O., Galanis, V., Gemelli, T., Meuth, S., Nagy, A., Greene, R.W., and Nestler, E.J. (2004) Essential role of BDNF in adult hippocampal function. Proc. Natl. Acad. Sci. USA 101:10827-10832.

2003

McClung, C.A. and Nestler, E.J. (2003) Regulation of gene expression and cocaine reward by CREB and ΔFosB. Nature Neurosci. 6(11):1208-1215.
Zachariou, V., Georgescu, D., Sanchez, N., Rahman, Z., DiLeone, R., Berton, O., Simon, M., Neve, R.L., Sim-Selley, L.J., Selley, D.E., Gold, S.J., and Nestler, E.J. (2003) Essential role for RGS9 in opiate action. Proc. Natl. Acad. Sci. USA 100:13656-13661.
Rahman, Z., Schwarz, J., Zachariou, V., Gold, S.J., Wein, M., Choi, K.H., et al. (2003) RGS9 modulates dopamine signaling in striatum. Neuron, 38:941-952.

2002

Barrot, M., Olivier, J.D.A., Perrotti, L.I., Impey, S., Storm, D.R,, Neve, R.L., Zachariou, V., & Nestler, E.J. (2002) CREB activity in the nucleus accumbens shell controls gating of behavioral responses to emotional stimuli. Proc. Natl. Acad. Sci. USA 99:11435-11440.
Nestler, E.J., Barrot, M., DiLeone, R.J., Eisch, A.J., Gold, S.J., and Monteggia, L.M. (2002) Neurobiology of depression. Neuron 34:13-25.

2001

Nestler, E.J. (2001) Molecular basis of neural plasticity underlying addiction. Nature Rev. Neurosci. 2:119-128.

1999

  Kelz, M.B., Chen, J.S., Carlezon, W.A., Whisler, K., Gilden, L., Beckmann, A.M., Steffen, C., Zhang, Y.-J., Marotti, L., Self, D.W., Tkatch, R., Baranauskas, G., Surmeier, D.J., Neve, R.L., Duman, R.S., Picciotto, M.R., and Nestler, E.J. (1999) Expression of the transcription factor ΔFosB in the brain controls sensitivity to cocaine. Nature 401:272-276.

1998

Carlezon, W.A., Jr., Thome, J., Olson, V.G., Lane-Ladd, S.B., Brodkin, E.S., Hiroi, N., Duman, R.S., Neve, R.L., and Nestler, E.J. (1998) Regulation of cocaine reward by CREB. Science 282:2272-2275.

1997

Carlezon, W.A., Jr., Boundy, V.A., Haile, C.N., Kalb, R.G., Neve, R., and Nestler, E.J. (1997) Sensitization to morphine induced by viral-mediated gene transfer. Science 277:812-814.
Nestler, E.J. and Aghajanian, G.K. (1997) Molecular and cellular basis of addiction. Science 278:58-63.

1996

Self, D.W., Barnhart, W.J., Lehman, D.A., and Nestler, E.J. (1996) Opposite modulation of cocaine-seeking behavior by D1-like and D2-like dopamine receptor agonists. Science 271:1586-1589.

1994

Hope, B.T., Nye, H.E., Kelz, M.B., Self, D.W., Iadarola, M.J., Nakabeppu, Y., Duman, R.S., and Nestler, E.J. (1994) Induction of a long-lasting AP-1 complex composed of altered Fos-like proteins in brain by chronic cocaine and other chronic treatments. Neuron 13:1235-1244.

1993

Nestler, E.J., Hope, B.T., and Widnell, K.L. (1993) Drug addiction: A model for the molecular basis of neural plasticity. Neuron 11:995-1006.

BOOKS

  Nestler, E.J. and Greengard, P. (1984) Protein Phosphorylation in the Nervous System, J. Wiley & Sons, New York.
Hyman, S.E. and Nestler, E.J. (1993) The Molecular Foundations of Psychiatry, American Psychiatric Press, Washington, D.C.
  Goldstein, A. and Nestler, E.J. (Eds.) (1998) Special Issue: Neurobiology of Addiction. Drug and Alcohol Dependence, vol. 51, numbers 1 and 2.
Charney, D.S. and Nestler, E.J. (Eds.) (2009) Neurobiology of Mental Illness, 3rd Ed., Oxford University Press, New York. (1st edition published in 1999, 2nd ed. in 2003.)
Nestler, E.J., Hyman, S.E., and Malenka, R.C (2009) Molecular Neuropharmacology: A Foundation for Clinical Neuroscience, 2nd Ed., McGraw-Hill, New York. (1st edition published in 2001.)
Rosenberg, R.N., DiMauro, S., Paulson, H.L., Ptacek, L., and Nestler, E.J. (Eds.) (2008) The Molecular and Genetic Basis of Neurologic and Psychiatric Disease, 4th Ed, Lippincott, Williams and Wilkins, New York. (3rd edition published in 2003.)
   
Nestler Laboratory
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