Behavioral Models of Addiction

To understand the relationship between a particular drug- or stress-induced molecular change andaddiction or depression, we study animals, in which the molecular change is mimicked or blocked, in behavioral models of these disorders. Accordingly, our research group maintains a Behavioral Testing Core Facility, which offers a wide battery of behavioral tests in rats and mice. In addition to assessing the general neurological function of the animal, we have tests that measure drug and non-drug reward (including sexual and feeding behavior), depression- and anxiety-like behavior, and cognitive function. More sophisticated tests of addiction, including drug self-administration and animal models of relapse, are also available. Together, we can formulate highly specific hypotheses concerning how a change in a particular protein within a given brain reward region causes certain aspects of addiction.

See under glossary, the following tests available:

Brain stimulation reward
Conditioned place preference
Self - administration


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