russo lab

The lab uses a wide variety of experimental approaches to understand how the brain adapts to stress and drugs leading to altered synaptic connectivity and behavioral changes relevant to depression and addiction.  We do this by integrating well-established behavioral models, with molecular and biochemical techniques and traditional neuroanatomy.

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Scott Russo, PhD
The goal of our research is to understand the molecular mechanisms of neuropsychiatric disorders such as depression and drug addiction. We use a combination of mouse stress models, molecular methods, and optogenetics to understand how the brain adapts to stress to control pathological behaviors.
  Click here for more publications→ Meet the team →
Johnson & Johnson / IMHRO Rising Star Translational Research Award winner, explains his lab's discoveries connecting depressionwith the immune system, suggesting a new physiological avenue for research into more effective depression therapies. For the 30% of depression sufferers who do not respond to conventional brain-centric medications, this could be very big. Recorded at IMHRO's Music Festival for Mental Health 2012.
Listen to Dr. Russo's podcast

"Depression might be an allergic reaction to stress."
Georgia Hodes, PhD, talks with Anna Maria Tremonti on The Current.