CDRB Laboratories & Facilities


   The Department of Cell, Developmental & Regenerative Biology explores the events governing the organization, structure and function of cells, tissues, and organisms, with a focus on the development, regeneration, and patterning of organs. To achieve this we are using a multitude of model organisms, including mouse, Drosophila, zebrafish, and Xenopus. Furthermore, our mission is to instruct medical and graduate students in the diverse aspects of biological sciences, with focus in cell and developmental biology and stem cell biology.

The department has currently 25 primary faculty and several secondary faculty, all participating in our scientific programs and seminar series. In addition, we are providing the institution with core facilities that allow the use of model organisms in any context of basic research, and translational and clinical research, and we provide the school with a high content screening facility for cell based assays.

    The main areas of research are focused on signaling pathways (Drosophila, mouse, Xenopus, zebrafish), cell death (Drosophila), organogenesis (Drosophila, mouse, zebrafish), fertilization (mouse), stem cells (mouse, zebrafish), and cancer models (Drosophila, mouse). In addition, several labs are using model organisms and cell culture assays in genomic and/or drug screens. For example, Drosophila is being used to screen for new drugs in the contexts of cancer and diabetes, or mouse and Drosophila are being employed in modeling the behavior of cancer cells and progression of tumors. 

    The study of biological mechanisms through a broad and multi-tiered approach reveals the unifying principles of biological development, structure and function with exquisite clarity, and provides important links to medical disorders and therapeutic potential. The graduate students and postdoctoral fellows are trained in these principles through their participation in a series of seminar series, rigorous lab work, and multidisciplinary approaches to interesting questions in biomedical research. Our faculty members are fully committed to providing a highly interactive, cutting-edge environment for postdoctoral fellows, MSTP and Ph.D. student training that develops creative and independent scientists. Many faculty members of the department are closely associated with the Black Family Stem Cell Institute (BFSCI), the Tisch Cancer Institute, and the Center for Molecular Cardiology at the School of Medicine. Collaborations between laboratories using different model organisms and systems are common and postdoctoral fellows and graduate students are an integral part of this process. The department fosters collaborations with faculty in other basic science departments as well as with clinical scientists through joint projects, seminars, interdisciplinary  programs, and training grants.

    The Department of Cell, Developmental & Regenerative Biology occupies the 25th floor and parts of the 18th floor of the Annenberg Building and the 7th floor and part of 3rd floor of the Atran Building.


Oneida Cintron



1468 Madison Avenue

Annenberg Building

25th Floor, Room 25-60

New York, NY 10029

mailing address:

Icahn School of Medicine at Mount Sinai

One Gustave L. Levy Place

Box 1020

New York, NY 10029-6574

fax: 212-860-9279

or send us an e-mail

directions & maps:

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Bieker Lab

Red blood cell differentiation.

Blenkinsop Lab

Retina disease and regeneration.

Cagan Lab

Disease/Development in Drosophila.

Cai Lab

Heart development & regeneration.

Chess Lab

Regulating gene expression.

Dubois Lab

Stem cells to model heart development.

Ezhkova Lab

Epigenetic regulation in stem cells.

Ghaffari Lab

Blood and blood disorders.

Gouon-Evans Lab

Liver development and regeneration.

Krauss Lab

Adhesion/signaling in development.

Mlodzik Lab

Wnt-Frizzled signaling & cell polarity.

Marlow Lab

Germline stem cells, fertility & polarity.

Moore Lab

Hematopoietic SCs and their niche.

Rendl Lab

Stem cell niche formation.

Sidi Lab

Cancer Target Discovery in Zebrafish.

Sokol Lab

Cell polarity and signaling.

Soriano Lab

Vertebrate developmental signaling.

Wang Lab

Pluripotency network in ES cells.

Wassarman Lab

Mammalian fertilization.

Zwaka Lab

Pluripotency and Multicellularity

For research, adjunct and secondary faculties click here.


Human Embryonic Stem Cell

Induced Pluripotent Stem Cell


D’Souza, Sunita L., Director.

Mouse Genetics (MG-SRF)

Kelley, Kevin A., Director.